TB-500 in the GLOW Stack: What It Adds

TB-500 is the most expensive single vial in Real Peptides' GLOW lineup at $48.00 for 10 mg, or $4.80 per mg, yet inside the $86.40 GLOW Stack the same 10 mg comes bundled with BPC-157 and GHK-Cu. TB 500 is one of the two peptides that GLOW shares with the Wolverine stack, and it carries the same regulatory and sport restrictions as its partner, BPC-157.

I compare these vendors and their COAs, so this page sticks to what TB-500 is, why bundles pair it the way they do, where to buy it and what FDA and WADA have said. TB-500 is not an FDA-approved drug; research vendors sell it for research use only.

TB-500 is a synthetic fragment related to thymosin beta-4

TB-500 is a synthetic peptide fragment related to thymosin beta-4, a protein the body makes naturally. The vial is not the full natural protein, which is a point vendor names like "TB-500 (Thymosin Beta-4)" can blur.

Its research sits in tissue-repair animal models. Human data is limited, and there are no controlled human trials that establish a benefit. Like the other GLOW components, every claim about TB-500 should be read as an animal or lab result unless a source says otherwise. The benefits page sets it beside GHK-Cu and BPC-157.

Why bundles pair TB-500 with BPC-157

Vendors pair TB-500 with BPC-157 because the two are described as working through different repair pathways in animal research. That pairing is common enough that the duo has its own market name, the Wolverine stack.

The logic is drawn from separate studies of each peptide, not from controlled work that tested them together. The same applies when GHK-Cu is added to make the GLOW Stack. Real Peptides' own listing for the single TB-500 vial notes as a con that it is "not BPC-157, a separate peptide," which is a fair reminder that each compound has its own evidence and its own unknowns.

TB-500 prices: single vials versus bundles

Among the TB 500 listings we track, the peptide is cheapest per milligram inside a bundle and most expensive as a Real Peptides single. Here is every TB-500 option in our comparison.

Because the Wolverine Peptide Stack costs less than the single TB-500 vial and also includes BPC-157, buying TB-500 alone at Real Peptides only makes sense if Wolverine is out of stock. Full numbers are on glow peptide cost.

Regulation: Category 2 in 2023, a panel vote in 2026

TB-500 was placed in Category 2 of FDA's interim bulk-substances lists in September 2023, which barred compounding pharmacies from using it while FDA reviewed safety concerns. That is the same status BPC-157 received.

On 23 July 2026, FDA's Pharmacy Compounding Advisory Committee voted 8-6, with one abstention, to recommend adding TB-500 to the 503A bulks list. The vote is non-binding. FDA must decide, then go through proposed and final rulemaking with public comment, and as of the July meeting TB-500 had not been added. TB-500 was also not among the products named in FDA's August 2026 warning letters to online peptide vendors. Details on each component are on the FDA status page.

WADA ban and other limits

TB-500 is prohibited in sport: the WADA Prohibited List covers thymosin beta-4 and its fragments. Athletes subject to testing should not use it, and that applies to every bundle that contains it, including GLOW.

Beyond sport, the practical limits are the ones that apply to the whole category. There is no approved human dose, and we do not publish any preparation or use guidance; see why there is no approved protocol. Product quality also varies, so check that the COA names TB-500, shows a lot number and matches your vial. Anyone thinking about a compound like this for their own health should talk to their doctor first.